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NAD+ and Metabolic Health By blocking NNMT, 5-Amino-1MQ increases intracellular NAD+ —a molecule essential for: Mitochondrial energy production DNA repair Healthy aging Sirtuin activation Fat oxidation In essence, this peptide helps your cells burn fat for fuel , especially in metabolically stubborn areas like the belly and flanks

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Blocking NNMT keeps nicotinamide in the NAD+ salvage pathway and S-adenosylmethionine available for polyamine synthesis, and in mouse models of diet-induced obesity that translates into smaller adipocytes, lower adipose mass, better oral glucose tolerance and less hepatic steatosis, with no measurable change in food intake